The Gut as a Model in Cell and Molecular Biology

Author: F. Halter
Publisher: Springer Science & Business Media
Size: 54.12 MB
Format: PDF, ePub
Category : Medical
Pages : 324
The Gut as a Model in Cell and Molecular Biology GET EBOOK
There are many separate groups working in gut biology, and they feel that the gut is an excellent model for investigating general problems in differentiation, growth control, stem cell biology, and regeneration and adaptive responses. There is a pressing need to define the objectives of the next 5 to 10 years, and the meeting, Part III of the Gastroenterology Symposia Freiburg 1996 (Falk Symposium No. 94), held in Freiburg, Germany, October 25-26, brought together some of these groups with a view to identifying areas which are not being utilized and need to be exploited, such as transgenic and knockout approaches, retrovirus delivery systems, and model cell/tissue systems. The main themes of the book are gastrointestinal development and differentiation, gut stem cell biology, and the control of gut growth in normal and abnormal situations. Basic research findings are related to clinical situations, and the book will appeal not only to gut cell and molecular biologists, but also to gastroenterologists interested in the potential applications of these subject areas.
RELATED BOOKS
The Gut as a Model in Cell and Molecular Biology
Language: en
Pages: 324
Authors: F. Halter, D. Winton, N.A. Wright
Categories: Medical
Type: BOOK - Published: 1997-12-31 - Publisher: Springer Science & Business Media

There are many separate groups working in gut biology, and they feel that the gut is an excellent model for investigating general problems in differentiation, growth control, stem cell biology, and regeneration and adaptive responses. There is a pressing need to define the objectives of the next 5 to 10 years, and the meeting, Part III of the Gastroenterology Symposia Freiburg 1996 (Falk Symposium No. 94), held in Freiburg, Germany, October 25-26, brought together some of these groups with a view to identifying areas which are not being utilized and need to be exploited, such as transgenic and knockout approaches, retrovirus delivery systems, and model cell/tissue systems. The main themes of the book are gastrointestinal development and differentiation, gut stem cell biology, and the control of gut growth in normal and abnormal situations. Basic research findings are related to clinical situations, and the book will appeal not only to gut cell and molecular biologists, but also to gastroenterologists interested in the potential applications of these subject areas.
The Gut as a Model in Cell and Molecular Biology
Language: en
Pages: 324
Authors: F. Halter, D. Winton, N.A. Wright
Categories: Medical
Type: BOOK - Published: 1997-12-31 - Publisher: Springer

There are many separate groups working in gut biology, and they feel that the gut is an excellent model for investigating general problems in differentiation, growth control, stem cell biology, and regeneration and adaptive responses. There is a pressing need to define the objectives of the next 5 to 10 years, and the meeting, Part III of the Gastroenterology Symposia Freiburg 1996 (Falk Symposium No. 94), held in Freiburg, Germany, October 25-26, brought together some of these groups with a view to identifying areas which are not being utilized and need to be exploited, such as transgenic and knockout approaches, retrovirus delivery systems, and model cell/tissue systems. The main themes of the book are gastrointestinal development and differentiation, gut stem cell biology, and the control of gut growth in normal and abnormal situations. Basic research findings are related to clinical situations, and the book will appeal not only to gut cell and molecular biologists, but also to gastroenterologists interested in the potential applications of these subject areas.
Cytokines and Cell Homeostasis in the Gastroinstestinal Tract
Language: en
Pages: 410
Authors: T. Andus, G. Rogler, K. Schlottmann, E. Frick, G. Adler, W. Schmiegel, J. Schölmerich, M. Zeitz
Categories: Medical
Type: BOOK - Published: 2000-11-30 - Publisher: Springer Science & Business Media

The gastrointestinal tract has a number of unique features. Its extensive surface is formed by a single layer of rapidly renewing cells, the intestinal epithelial cells. These cells are in contact with a number of other cell populations, including the largest part of the immune system, and with an excessive luminal antigen load, including vast numbers of bacteria. Furthermore two more organs, namely liver and pancreas, are part of the system. The rapid renewal of the epithelial layer, the interactions of different cell types, and the balance between cell proliferation and death, have been fascinating subjects of studies in recent years. Much has been learned, and cytokines have emerged as important mediators for all these interactions and homeostatic systems. This book, the proceedings of the Falk Symposium 113 on `Cytokines and Cell Homeostasis in the Gastrointestinal Tract', held in Regensburg, Germany, 16-18 September 1999, provides a forum for basic scientists and interested clinicians to exchange ideas, to discuss concepts and to plan further studies.
Model organisms in inflammation and cancer
Language: en
Pages: 83
Authors: Yiorgos Apidianakis, Dominique Ferrandon
Categories: Cancer
Type: BOOK - Published: 2014-12-17 - Publisher: Frontiers E-books

A link between inflammation and cancer was initially made by Rudolf Virchow back in the 19th century. Nowadays many cancers are considered dependent on inflammatory responses to microbial and damaged-self stimuli and both arms of immunity, innate and adaptive, are playing a role in promoting cancer. Moreover, besides environmental factors, opportunistic pathogens contribute to inflammation and cancer. Nevertheless, microbial influence on chronic disease is sometimes difficult to discern, especially in the context of polymicrobial communities, such as those found in the digestive tract. In this light, model organisms provide important insights into immune and growth signals that promote cancer, and suggest therapies that will selectively target potentially harmful microbes or modulate host responses. A number of review and opinion articles in this series address novel aspects and paradigms of the interactions between the microbiota and the host in relation to inflammation and cancer.
Models of Cellular Regulation
Language: en
Pages: 183
Authors: Baltazar Aguda, Avner Friedman, The Ohio State University Visiting Associate Professor
Categories: Mathematics
Type: BOOK - Published: 2008-07-31 - Publisher: Oxford University Press

This book illustrates the mechanisms and models linking the realms of molecular interactions and biological processes or functions. It addresses the need of mathematical modelers to learn how to formulate models of cellular processes and to understand how quantitative modeling can help sort through the complexities of molecular regulatory networks.
Culture of Human Tumor Cells
Language: en
Pages: 452
Authors: Roswitha Pfragner, R. Ian Freshney
Categories: Science
Type: BOOK - Published: 2005-03-11 - Publisher: John Wiley & Sons

This comprehensive resource provides stepwise protocols for the in vitro cultivation of the major types of human tumors. Written in a reader-friendly style, this book is organized by specific tumor, discussing cultures for lung, gastric, colorectal, pancreas, bladder, prostate, ovary, cervix, mammary carcinoma, myoepithelium, squamous, melanoma, lymphoma, glioma, and neuroendocrine tumors. Detailed techniques for initiation, propagation, and characterization of established cell lines are presented. Drug treatment, selection, differentiation, assays for malignant cells, risks, and applications are discussed. An extensive listing of vendors for equipment and other cell culture products is also included.
Agricultural Sciences for Human Sustainability
Language: en
Pages: 136
Authors: Graduate School of Agriculture, Hokkaido University, 北海道大学大学院農学研究院
Categories: Science
Type: BOOK - Published: 2012-06-30 - Publisher: Kaiseisha press

「食料・バイオマス生産」「環境保全」「食の安全・機能性」など、世界が直面する諸課題に対し、農学先進校・北大農学院の各分野ではどのような研究が行われているのか。札幌農学校精神を今に伝える「農学概論テキスト」。
Perinatal Stem Cells
Language: en
Pages: 373
Authors: Anthony Atala, Sean V. Murphy
Categories: Science
Type: BOOK - Published: 2014-08-28 - Publisher: Springer

This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology, and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, inflammatory disease, bone regeneration, pulmonary disease, and the treatment of spinal cord injury. Further, the book discusses current progress in the manufacturing, banking and clinical translation of perinatal stem cells. Through this book, readers will gain a thorough understanding of the current pre-clinical and clinical applications of perinatal stem cells as well as the efforts to support the transition of perinatal stem cell therapies from laboratories to clinics. Perinatal Stem Cells contains thirty-two chapters written by internationally recognized leaders in stem cell research. It is organized into four sections covering amniotic fluid stem cells, placental and placental membrane stem cells, umbilical cord stem cells, and clinical translation. This cohesive structure provides an effective framework for detailed insight into this new frontier. Edited by Dr. Anthony Atala, one of the foremost experts in the field, and his co-editor Dr. Sean V. Murphy, this volume is a definitive work for stem cell research and its future implications. It is a key resource for all stem cell researchers, clinicians, and government and industry staff working in this dynamic and exciting field.
Beneficial Microbes in Fermented and Functional Foods
Language: en
Pages: 600
Authors: Ravishankar Rai V, Jamuna A. Bai
Categories: Medical
Type: BOOK - Published: 2014-12-17 - Publisher: CRC Press

This book focuses exclusively on the beneficial effects of microbes in food. The section on traditional and modern fermented foods covers the role of microbes and their diversity in fermented foods, interaction between the different microflora present in fermented food products, development of starter cultures to improve the nutritional and sensory quality of fermented foods, and factors and processes affecting the safety of various fermented foods. The second section focuses on microbes in and as functional foods: probiotics, prebiotics and synbiotics.
Mechanisms of Regeneration
Language: en
Pages: 368
Authors: Ravishankar Rai V, Jamuna A. Bai
Categories: Science
Type: BOOK - Published: 2014-02-07 - Publisher: Academic Press

This new volume of Current Topics in Developmental Biology covers the area of mechanisms in regeneration. With an international board of authors, it provides a comprehensive set of reviews covering such topics as control of growth during regeneration, skeletal muscle degeneration and regeneration in mammals and flies, and suppression of regeneration in mammals. Covers the area of mechanisms in regeneration International board of authors Provides a comprehensive set of reviews
Molecular Biology of B Cells
Language: en
Pages: 600
Authors: Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt
Categories: Science
Type: BOOK - Published: 2014-10-09 - Publisher: Elsevier

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response
Physiology of the Gastrointestinal Tract, Two Volume Set
Language: en
Pages: 2308
Authors: Hamid M. Said
Categories: Medical
Type: BOOK - Published: 2012-07-04 - Publisher: Academic Press

Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations